原題:
[藥劑學(xué)]一病人單次靜脈注射某藥物10mg,半小時(shí)血藥濃度是 g/mL。(已知Tl/2=4h,V=60L)
選項(xiàng):
A.0.153
B.0.225
C.0.301
D.0.458
E.0.610
答案:
A
解析:
k=0.693/tl/2=0.693/4=0.173
logC= logC0一kt/2.303=log10/60一0.173*0.5/2.303
=-0.778一0.0375=一0.815
C=0.153